FKBP52抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
FKBP52抗体

FKBP52抗体

商家询价

产品名称： FKBP52抗体

英文名称： FKBP52Antibody

产品编号： XY10655-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 FKBP52抗体

Applications
In-house applications ELISA, WB, IHC, IF, IP, FC     Application not tested? Please see our Guarantee.
Published applications IHC, WB Publications 4 citations –view here
Species specificity Human, Mouse; other species not tested.
Published Species Human, mouse
Images
Prev12NextView more validation data
  • 10655-1-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 10655-1-AP(FKBP52 antibody) at dilution of 1:1000
  • 10655-1-AP;HeLa cellsIP Result of anti-FKBP52 (IP:10655-1-AP, 3ug; Detection:10655-1-AP 1:1000) with HeLa cells lysate 3000ug.
  • 10655-1-AP;human prostate cancerImmunohistochemical of paraffin-embedded human prostate cancer using 10655-1-AP(FKBP52 antibody) at dilution of 1:100 (under 25x lens)
  • 10655-1-AP;MCF-7Immunofluorescent analysis of MCF-7 cells, using FKBP4 antibody 10655-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
  • 10655-1-AP;MCF-7 cells1X10^6 MCF-7 cells were stained with 0.2ug FKBP52 antibody (10655-1-AP, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.
Positive WB detected in HeLa cells, Jurkat cells, NIH/3T3 cells, PC-3 cells
Positive IP detected in HeLa cells
Positive IHC detected in Human prostate cancer tissue
Positive IF detected in MCF-7 cells
Positive FC detected in MCF-7 cells
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:10-1:100
 FKBP52抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information FKBP52抗体
Immunogen FKBP52 fusion protein ag1019 Full name FK506 binding protein 4, 59kDa
Calculated molecular
weight		 59 kDa Observed molecular 
weight		 56-59 kDa
GenBank accession 
number		 BC007924 Gene ID (NCBI) 2288
Gene symbol FKBP4 Synonyms 51 kDa FK506 binding protein, 52 kDa FK506 binding protein, 52 kDa FKBP, 59 kDa immunophilin, FK506 binding protein 4, FK506 binding protein 4, 59kDa, FKBP 4, FKBP 52, FKBP4, FKBP51, FKBP52, FKBP59, HBI, HSP binding immunophilin, Hsp56, Immunophilin FKBP52, p52, p59, PPIase, PPIase FKBP4, Rotamase
Background

FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs, and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics, FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's, and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function, and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition, FKBP52 is likely to play a role in growth and development of the male genitalia. FKBP52抗体

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