MS4A2 monoclonal antibody (M02), clone 3B1
产品名称: MS4A2 monoclonal antibody (M02), clone 3B1
英文名称: MS4A2 monoclonal antibody (M02), clone 3B1
产品编号: H00002206-M02
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant MS4A2.
- Immunogen:
- MS4A2 (NP_000130, 1 a.a. ~ 59 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQE
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (32.23 KDa) .
- MSDS:
- Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of MS4A2 expression in transfected 293T cell line by MS4A2 monoclonal antibody (M02), clone 3B1.
Lane 1: MS4A2 transfected lysate(26.5 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged MS4A2 is 0.1 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 2206
- GeneBank Accession#:
- NM_000139
- Protein Accession#:
- NP_000130
- Gene Name:
- MS4A2
- Gene Alias:
- APY,ATOPY,FCER1B,FCERI,IGEL,IGER,IGHER,MS4A1
- Gene Description:
- membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of family members. Alternative splicing results in multiple transcript variants encoding different isoforms
- Other Designations:
- Fc IgE receptor, beta chain,Fc epsilon receptor I beta-chain,Fc-epsilon receptor I beta-chain,High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fc receptor, beta-subunit) (Fc epsilon receptor I beta-chain),IgE responsiveness (atopic)
- Gene Pathway
- Related Disease
- Angioneurotic Edema
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Brain Ischemia
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Calcinosis
- Cardiovascular Diseases
- Cerebrovascular Disorders
- Chlamydia Infections
- Chronic Disease
- Constriction, Pathologic
- Coronary Artery Disease
- Coronary Disease
- Dermatitis, Atopic
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2