SORL1 polyclonal antibody (A01)
产品名称: SORL1 polyclonal antibody (A01)
英文名称: SORL1 polyclonal antibody (A01)
产品编号: H00006653-A01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant SORL1.
- Immunogen:
- SORL1 (NP_003096, 82 a.a. ~ 181 a.a) partial recombinant protein with GST tag.
- Sequence:
- SAALQPEPIKVYGQVSLNDSHNQMVVHWAGEKSNVIVALARDSLALARPKSSDVYVSYDYGKSFKKISDKLNFGLGNRSEAVIAQFYHSPADNKRYIFAD
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
- MSDS:
- Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 6653
- GeneBank Accession#:
- NM_003105
- Protein Accession#:
- NP_003096
- Gene Name:
- SORL1
- Gene Alias:
- C11orf32,FLJ21930,FLJ39258,LR11,LRP9,SORLA,SorLA-1,gp250
- Gene Description:
- sortilin-related receptor, L(DLR class) A repeats-containing
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein that belongs to the families of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins, of low density lipoprotein receptor (LDLR) proteins, and of fibronectin type III repeats proteins. In addition to VPS10, LDLR and fibronectin type 3 domains, this protein also includes an epidermal growth factor precursor-like module, a single transmembrane segment and a cytoplasmic tail with features similar to endocytosis- and sorting-competent receptors. Members of the VPS10 domain-containing receptor family are large with many exons but the CDS lengths are usually less than 3700 nt; this gene is an exception to the pattern with a CDS length greater than 6600 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. The encoded protein is mainly intracellular and localizes in the paranuclear compartment. It is synthesized as a preproprotein, and when the propeptide is still attached, no binding occurs to the VPS10 domain. This gene is strongly expressed in the central nervous system. [provided by RefSeq
- Other Designations:
- mosaic protein LR11,sortilin-related receptor containing LDLR class A repeats
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Cardiovascular Diseases
- Cerebral Hemorrhage
- Cerebrovascular Disorders
- Cognition
- Cognition Disorders
- Dementia
- Diabetes Mellitus, Type 2
- Down Syndrome
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Intelligence Tests
- Nerve Degeneration
- Neuropsychological Tests
- Psychiatric Status Rating Scales
- Tobacco Use Disorder
- Werner syndrome