CYP3A4 MaxPab rabbit polyclonal antibody (D01)
产品名称： CYP3A4 MaxPab rabbit polyclonal antibody (D01)
英文名称： CYP3A4 MaxPab rabbit polyclonal antibody (D01)
产品编号： H00001576-D01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human CYP3A4 protein.
- Immunogen:
- CYP3A4 (AAI01632.1, 1 a.a. ~ 503 a.a) full-length human protein.
- Sequence:
- MALIPDLAMETWLLLAVSLVLLYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDGTVSGA
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- CYP3A4 MaxPab rabbit polyclonal antibody. Western Blot analysis of CYP3A4 expression in HepG2.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of CYP3A4 expression in transfected 293T cell line (H00001576-T01) by CYP3A4 MaxPab polyclonal antibody.
Lane 1: CYP3A4 transfected lysate(57.30 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunoprecipitation
- Immunoprecipitation of CYP3A4 transfected lysate using anti-CYP3A4 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with CYP3A4 purified MaxPab mouse polyclonal antibody (B01P) (H00001576-B01P).
- Protocol Download
- Entrez GeneID:
- 1576
- GeneBank Accession#:
- NM_017460.3
- Protein Accession#:
- AAI01632.1
- Gene Name:
- CYP3A4
- Gene Alias:
- CP33,CP34,CYP3A,CYP3A3,HLP,MGC126680,NF-25,P450C3,P450PCN1
- Gene Description:
- cytochrome P450, family 3, subfamily A, polypeptide 4
- Omim ID:
- 124010
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. [provided by RefSeq
- Other Designations:
- P450-III, steroid inducible,cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3,cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4,cytochrome P450, subfamily IIIA, polypeptide 4,glucocorticoid-inducible P450,nifedipine o
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- Acquired Immunodeficiency Syndrome
- Acute Disease
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