CNTFR polyclonal antibody
产品名称： CNTFR polyclonal antibody
英文名称： CNTFR polyclonal antibody
产品编号： PAB18803
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CNTFR.
- Immunogen:
- A synthetic peptide corresponding to 14 amino acids at internal region of human CNTFR.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Peptide affinity purification
- Storage Buffer:
- In buffer containing 0.02% sodium azide, 2% BSA
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:8000-1:30000)
Western Blot (1:50-1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- ELISA
- Entrez GeneID:
- 1271
- Gene Name:
- CNTFR
- Gene Alias:
- MGC1774
- Gene Description:
- ciliary neurotrophic factor receptor
- Omim ID:
- 118946
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified. [provided by RefSeq
- Other Designations:
- CNTFR alpha,OTTHUMP00000021270,OTTHUMP00000021271,ciliary neurotrophic factor receptor alpha