CDH13 polyclonal antibody
产品名称： CDH13 polyclonal antibody
英文名称： CDH13 polyclonal antibody
产品编号： PAB3081
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CDH13.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CDH13.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
Flow cytometry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma.
Tsou JA, Galler JS, Siegmund KD, Laird PW, Turla S, Cozen W, Hagen JA, Koss MN, Laird-Offringa IA.Mol Cancer. 2007 Oct 29;6:70.
- 2.
- Tumor-specific downregulation and methylation of the CDH13 (H-cadherin) and CDH1 (E-cadherin) genes correlate with aggressiveness of human pituitary adenomas.
Qian ZR, Sano T, Yoshimoto K, Asa SL, Yamada S, Mizusawa N, Kudo E.Mod Pathol. 2007 Dec;20(12):1269-77. Epub 2007 Sep 14.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis of CDH13 (arrow) using rabbit CDH13 polyclonal antibody (Cat # PAB3081). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDH13 gene (Lane 2) (Origene Technologies).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CDH13 polyclonal antibody (Cat # PAB3081) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 1012
- Protein Accession#:
- NP_001248;P55290
- Gene Name:
- CDH13
- Gene Alias:
- CDHH
- Gene Description:
- cadherin 13, H-cadherin (heart)
- Omim ID:
- 601364
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region but, unlike the typical cadherin superfamily member, lacks the highly conserved cytoplasmic region. This particular cadherin is a putative mediator of cell-cell interaction in the heart and may act as a negative regulator of neural cell growth. The gene locus is hypermethylated or deleted in breast, ovarian and lung cancers. Two major mRNA transcripts encoding identical proteins are found, products of alternative polyadenylation sites. [provided by RefSeq
- Other Designations:
- H-cadherin,P105,T-cad,T-cadherin,cadherin 13,heart-cadherin,truncated-cadherin
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