FITC标记的溶质载体转运蛋白家族30成员5抗体
产品名称： FITC标记的溶质载体转运蛋白家族30成员5抗体
英文名称： Anti-SLC30A5/FITC
产品编号： HZ-21254R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SLC30A5/FITC Conjugated antibody
FITC标记的溶质载体转运蛋白家族30成员5抗体
| 英文名称 | Anti-SLC30A5/FITC |
| 中文名称 | FITC标记的溶质载体转运蛋白家族30成员5抗体 |
| 别 名 | DKFZp686F23142; FLJ12496; FLJ12756; hZTL1; MGC5499; Putative uncharacterized protein DKFZp686F23142; Slc30a5; Solute carrier family 30 (zinc transporter) member 5; Solute carrier family 30 (Zinc transporter), member 5 isoform CRA a; Solute carrier family 30 member 5; Zinc transporter 5; Zinc transporter ZnT 5; Zinc transporter ZTL1; ZNT 5; ZnT-5; ZnT-like transporter 1; ZNT5; ZNT5_HUMAN; ZNTL 1; ZNTL1; ZTL 1; ZTL1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 转运蛋白 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 84kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLC30A5 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the SLC30A/ZnT family of zinc transporter proteins. ZnT proteins mediate both cellular zinc efflux and zinc sequestration into membrane-bound organelles. The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6, and may also regulate zinc sequestration into secretory granules of pancreatic beta cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Oct 2011] Function: Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP. Subunit: Heterooligomer. Interacts with ZNT6. Subcellular Location: Golgi apparatus > trans-Golgi network membrane. Perimeter of granules, localizes to the brush border membrane of the enterocyte. Concentrated in early compartments of the secretory pathway such as COPII-coated vesicles. Tissue Specificity: Ubiquitously expressed. Highly expressed in pancreas, liver and kidney. Expressed abundantly in insulin-containing beta cells, undetectable in other endocrine cell types including glucagon-secreting alpha cells and most acinar cells. Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. Database links: Entrez Gene: 64924 Human Omim: 607819 Human SwissProt: Q8TAD4 Human SwissProt: Q9BVY8 Human Unigene: 631975 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
该基因编码ScC30A/ZnT家族的锌转运蛋白。ZnT蛋白介导细胞锌流出和锌固定到膜结合的细胞器内。该编码蛋白作为具有锌转运蛋白6的异二聚体，在早期的分泌途径中发挥作用，还可能调节锌在胰腺β细胞分泌颗粒中的螯合。已观察到该基因的另一种剪接转录体变体，编码多种异构体，该基因的一个假基因位于19号染色体的长臂上。[ RefSeq，OCT 2011提供]