IRF8 polyclonal antibody
产品名称： IRF8 polyclonal antibody
英文名称： IRF8 polyclonal antibody
产品编号： PAB12937
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of IRF8.
- Immunogen:
- A synthetic peptide corresponding to C-terminus 16 amino acids of human IRF8.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Induction and regulation of IFNs during viral infections.
Malmgaard L.J Interferon Cytokine Res. 2004 Aug;24(8):439-54.
- 2.
- Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells.
Tsujimura H, Tamura T, Kong HJ, Nishiyama A, Ishii KJ, Klinman DM, Ozato K.J Immunol. 2004 Jun 1;172(11):6820-7.
- 3.
- Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription.
Nelson N, Marks MS, Driggers PH, Ozato K.Mol Cell Biol. 1993 Jan;13(1):588-99.
- Entrez GeneID:
- 3394
- Protein Accession#:
- NP_002154
- Gene Name:
- IRF8
- Gene Alias:
- H-ICSBP,ICSBP,ICSBP1,IRF-8
- Gene Description:
- interferon regulatory factor 8
- Omim ID:
- 601565
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq
- Other Designations:
- interferon consensus sequence binding protein 1