ESR1 monoclonal antibody, clone 1D5
产品名称： ESR1 monoclonal antibody, clone 1D5
英文名称： ESR1 monoclonal antibody, clone 1D5
产品编号： MAB3563
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant ESR1.
- Immunogen:
- Recombinant protein corresponding to human ESR1.
- Host:
- Mouse
- Theoretical MW (kDa):
- 67
- Reactivity:
- Human, Rat
- Specificity:
- This antibody reacts with N-terminal 67 KDa polypeptide of the human ESR1.
- Form:
- Liquid
- Concentration:
- 50 ug/mL
- Isotype:
- IgG1
- Storage Buffer:
- In phosphate buffer, pH 7.3 (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Recommend Usage:
- Immunohistochemistry (1:20-1:25)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Immunohistochemical determination of oestrogen receptor: comparison of different methods of assessment of staining and correlation with clinical outcome of breast cancer patients.
Barnes DM, Harris WH, Smith P, Millis RR, Rubens RD.Br J Cancer. 1996 Nov;74(9):1445-51.
- 2.
- Demonstration of oestrogen receptors in paraffin wax sections of breast carcinoma using the monoclonal antibody 1D5 and microwave oven processing.
Sannino P, Shousha S.J Clin Pathol. 1994 Jan;47(1):90-2.
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Entrez GeneID:
- 2099
- Gene Name:
- ESR1
- Gene Alias:
- DKFZp686N23123,ER,ESR,ESRA,Era,NR3A1
- Gene Description:
- estrogen receptor 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq
- Other Designations:
- OTTHUMP00000017718,OTTHUMP00000017719,estrogen receptor alpha
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Acute Disease
- Adenocarcinoma
- Alveolar Bone Loss
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Anorexia Nervosa
- Antisocial Personality Disorder
- Aortic Aneurysm, Abdominal
- Arteriosclerosis
- Arthritis, Juvenile Rheumatoid
- Asperger Syndrome
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Atrial Fibrillation