磷酸化Ephrin B抗体
产品名称： 磷酸化Ephrin B抗体
英文名称： phospho-Ephrin B (Tyr324 + Tyr329)
产品编号： hz-3129R
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 IF=1:100-500
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Rabbit Anti-phospho-Ephrin B (Tyr324 + Tyr329) antibody
| 产品编号 | hz-3129R |
| 英文名称 | phospho-Ephrin B (Tyr324 + Tyr329) |
| 中文名称 | 磷酸化Ephrin B抗体 |
| 别 名 | Ephrin B (phospho Y324); p-Ephrin B (phospho Y324); Ephrin B (phospho Y329); p-Ephrin B (phospho Y329); phospho-Ephrin B1(Tyr324+Tyr329); phospho-Ephrin B2 (Tyr311+Tyr316); CEK5 ligand; EFNB1; ELK L; EphrinB; Ephrin-B; ELK ligand; ELKL; EPH related receptor tyrosine kinase ligand 2; Ephrin B Precursor; Ephrin B1; Ephrin B2; LERK 2; LERK2; EFNB1_HUMAN; EFNB2_HUMAN. |
| 产品类型 | 磷酸化抗体 |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 36kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human Ephrin B around the phosphorylation site of Tyr324/329:GD(p-Y)GHPV(p-Y)IV |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase. Subunit: Interacts with GRIP1 and GRIP2. Binds to Nipah virus G protein. Subcellular Location: Membrane; single pass type I membrane protein. Tissue Specificity: Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments. Similarity: Belongs to the ephrin family. Contains 1 ephrin RBD (ephrin receptor-binding) domain. SWISS: P98172 Gene ID: 1947 Database links: Entrez Gene: 1947 Human Entrez Gene: 1948 Human Entrez Gene: 13641 Mouse Entrez Gene: 13642 Mouse Entrez Gene: 25186 Rat Omim: 300035 Human Omim: 600527 Human SwissProt: P52799 Human SwissProt: P98172 Human SwissProt: P52795 Mouse SwissProt: P52800 Mouse SwissProt: P52796 Rat SwissProt: Q6P7B6 Rat Unigene: 144700 Human Unigene: 149239 Human Unigene: 44398 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |