FITC标记的细胞分化蛋白SEP1抗体
产品名称： FITC标记的细胞分化蛋白SEP1抗体
英文名称： Anti-SEPT1/FITC
产品编号： HZ-7769R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-SEPT1/FITC Conjugated antibody
FITC标记的细胞分化蛋白SEP1抗体
| 英文名称 | Anti-SEPT1/FITC |
| 中文名称 | FITC标记的细胞分化蛋白SEP1抗体 |
| 别 名 | DIFF6; Differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase); LARP; Peanut like protein 3; PNUTL3; SEP1; Septin 1; Septin1; Serologically defined breast cancer antigen NY BR 24; SEPT1_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 神经生物学 信号转导 细胞周期蛋白 细胞分化 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SEPT1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SEPT1 is a member of the septin family of GTPases. Members of this family are required for cytokinesis. SEPT1 is associated with the tau-based paired helical filament core, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Function: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). Subunit: Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity). Interacts with AURKB. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton. Tissue Specificity: Expressed at high levels in lymphoid and haematopoietic tissues. Similarity: Belongs to the septin family. Database links: Entrez Gene: 1731 Human Entrez Gene: 54204 Mouse Entrez Gene: 293507 Rat Omim: 612897 Human SwissProt: Q8WYJ6 Human SwissProt: P42209 Mouse SwissProt: Q5EB96 Rat Unigene: 632176 Human Unigene: 18 Mouse Unigene: 68675 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. SEPTIN(SEPT)家族是细胞骨架蛋白的一种，具有GTPase的活性。经研究发現，SEPT参与细胞核分裂、细胞膜的运输以及构成细胞骨架 |
SEPT1是GTP酶家族的一个成员。这个家族的成员需要胞质分裂。SEPT1与Tau基配对的螺旋丝核相关，并可能参与阿尔茨海默病中神经纤维缠结的形成。