FITC标记的血管生成素相关蛋白5
产品名称： FITC标记的血管生成素相关蛋白5
英文名称： Anti-ANGPTL5/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-ANGPTL5/FITC Conjugated antibody
FITC标记的血管生成素相关蛋白5
| 英文名称 | Anti-ANGPTL5/FITC |
| 中文名称 | FITC标记的血管生成素相关蛋白5 |
| 别 名 | Angiopoietin like 5; Angiopoietin related protein 5; Angiopoietin-like protein 5; Angiopoietin-related protein 5; ANGL5_HUMAN; ANGPTL 5; ANGPTL5; Fibrinogen like; hide |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 生长因子和激素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Chicken, Pig, Horse, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ANGPTL5 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Angptl5 (angiopoietin-like 5) is a 388 amino acid secreted protein that contains one fibrinogen C-terminal domain and is primarily expressed in adult heart tissue. The gene encoding Angptl5 maps to human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. Subcellular Location: Secreted (Potential). Tissue Specificity: Mainly expressed in adult heart. Similarity: Contains 1 fibrinogen C-terminal domain. Database links: Entrez Gene: 253935 Human Omim: 607666 Human SwissProt: Q86XS5 Human Unigene: 318370 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
AngPTL5（血管生成素样5）是一种388氨基酸分泌蛋白，含有一个纤维蛋白原C-末端结构域，主要在心脏组织中表达。编码ANGPTL5的基因映射到人类第11号染色体。大约有1亿3500万个碱基对和1400个基因，染色体11包括大约4%的人类基因组DNA，并且被认为是基因和疾病关联密集染色体。11号染色体编码ATM基因是调控双链DNA断裂后细胞周期阻滞和凋亡的重要因素。ATM突变导致称为共济失调毛细血管扩张症。血液病镰状细胞贫血和地中海贫血是由HBB基因突变引起的，而WalMS瘤、WAGR综合征和Duny-Drasy综合征与WT1基因突变有关。Jurvl和Lange Nielsen综合征、杰克布森综合征、尼曼匹克病、遗传性血管水肿和Smith-LeMi-Opz综合征也与11号染色体编码基因的缺陷有关。