FBXW7 polyclonal antibody (A01)-抗体-抗体-生物在线
亚诺法生技股份有限公司（Abnova)
FBXW7 polyclonal antibody (A01)

FBXW7 polyclonal antibody (A01)

商家询价

产品名称： FBXW7 polyclonal antibody (A01)

英文名称： FBXW7 polyclonal antibody (A01)

产品编号： H00055294-A01

产品价格： null

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)
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进入展台

  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a partial recombinant FBXW7.
  • Immunogen:
  • FBXW7 (NP_361014, 599 a.a. ~ 707 a.a) partial recombinant protein with GST tag.
  • Sequence:
  • ADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00055294-A01
    Western Blot detection against Immunogen (38.1 KDa) .
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • FBXW7 polyclonal antibody (A01), Lot # 051026JC01 Western Blot analysis of FBXW7 expression in Jurkat ( Cat # L017V1 ).
  • Protocol Download
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Gene Name:
  • FBXW7
  • Gene Alias:
  • AGO,CDC4,DKFZp686F23254,FBW6,FBW7,FBX30,FBXO30,FBXW6,FLJ16457,SEL-10,SEL10
  • Gene Description:
  • F-box and WD repeat domain containing 7
  • Gene Summary:
  • This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila),F-box protein FBW7,F-box protein SEL-10,archipelago homolog,archipelago, Drosophila, homolog of,homolog of C elegans sel-10

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