FITC标记的三磷酸腺苷结合盒转运蛋白9抗体
产品名称： FITC标记的三磷酸腺苷结合盒转运蛋白9抗体
英文名称： Anti-ABCA9/FITC
产品编号： HZ-7853R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-ABCA9/FITC Conjugated antibody
FITC标记的三磷酸腺苷结合盒转运蛋白9抗体
| 英文名称 | Anti-ABCA9/FITC |
| 中文名称 | FITC标记的三磷酸腺苷结合盒转运蛋白9抗体 |
| 别 名 | ATP binding cassette A9; ATP binding cassette sub family A (ABC1) member 9; ATP binding cassette sub family A member 9; DKFZp686F2450; EST640918; MGC75415; ABCA9_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 信号转导 细胞周期蛋白 细胞分化 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Horse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 184kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ABCA9 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: ABCA9 is a member of the superfamily of ATP-binding cassette (ABC) transporters and contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ABCA9 is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of the ABCA9 gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. ABCA9 May play a role in monocyte differentiation and lipid homeostasis. Function: May play a role in monocyte differentiation and lipidhomeostasis. Subcellular Location: Membrane; Multi-pass membrane protein(Potential). Tissue Specificity: Widely expressed with higher expression inheart. Similarity: Belongs to the ABC transporter superfamily. ABCAfamily. Contains 2 ABC transporter domains. Database links: Entrez Gene: 10350 Human Entrez Gene: 217262 Mouse Entrez Gene: 287788 Rat Omim: 612507 Human SwissProt: Q8IUA7 Human SwissProt: Q8K449 Mouse Unigene: 131686 Human Unigene: 291459 Mouse Unigene: 98251 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
ABCA9是ATP结合盒（ABC）转运蛋白超家族的成员，包含两个跨膜结构域和两个核苷酸结合折叠体。ABC蛋白通过跨膜和胞内膜运输各种分子。ABC基因分为七个不同的亚家族（ABC1、MDR/TAP、MRP、ALD、OABP、GCN20和White）。ABCA9是ABC1亚家族的成员，在17q24号染色体上与其他四个ABC1家族成员聚集。在单核细胞分化为巨噬细胞时，ABCA9基因的转录表达受到胆固醇导入的抑制。ABCA9可能在单核细胞分化和脂质稳态中发挥作用。