FITC标记的神经调节蛋白4抗体
产品名称： FITC标记的神经调节蛋白4抗体
英文名称： Anti-NRG4/FITC
产品编号： HZ-19348R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NRG4/FITC Conjugated antibody
FITC标记的神经调节蛋白4抗体
| 英文名称 | Anti-NRG4/FITC |
| 中文名称 | FITC标记的神经调节蛋白4抗体 |
| 别 名 | DKFZp779N0541; DKFZp779N1944; Heregulin 4; HRG4; Neuregulin 4; Neuregulin-4; NRG-4; NRG4; NRG4_HUMAN; pro-neuregulin-4, membrane-bound isoform; Pro-NRG4. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 13kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NRG4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM, Mar 2008] Function: Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors. Subcellular Location: Secreted and Cell membrane. Does not seem to be active. Post-translational modifications: Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form. Extensive glycosylation precedes the proteolytic cleavage. Similarity: Belongs to the neuregulin family. Contains 1 EGF-like domain. Database links: Entrez Gene: 145957 Human Entrez Gene: 83961 Mouse Entrez Gene: 690919 Rat Omim: 610894 Human SwissProt: Q8WWG1 Human SwissProt: Q9WTX4 Mouse Unigene: 732438 Human Unigene: 443874 Mouse Unigene: 120491 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
《神经调节蛋白类，包括nrg4 Activate 1型，生长因子受体（EGFR 131550看到；MIM）两个启动细胞的两个细胞信号转导通（酪氨酸phosphorylation Harari等人，1999年10348342 [医学]）。[ supplied OMIM的城市，2008年3月）