FITC标记的趋化因子受体D6抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的趋化因子受体D6抗体

FITC标记的趋化因子受体D6抗体

商家询价

产品名称： FITC标记的趋化因子受体D6抗体

英文名称： Anti-Chemokine Receptor D6/FITC

产品编号： HZ-13897R-FITC

产品价格： null

产品产地： 中国/上海

品牌商标： HZbscience

更新时间： 2023-08-17T10:24:20

使用范围： ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-Chemokine Receptor D6/FITC Conjugated antibody 

FITC标记的趋化因子受体D6抗体

 

英文名称 Anti-Chemokine Receptor D6/FITC
中文名称 FITC标记的趋化因子受体D6抗体
别    名 C C chemokine receptor D6; C-C chemokine receptor D6; CC chemokine binding receptor JAB61; CC chemokine receptor D6; CCBP 2; CCBP2; ACKR2_HUMAN; CCR 10; CCR 9; CCR10; CCR9; Chemokine (C C motif) receptor 9; Chemokine (C C) receptor 9; Chemokine binding protein 2; Chemokine binding protein D6; Chemokine C C motif receptor 9; Chemokine C C receptor 9; Chemokine CC motif receptor 9; Chemokine CC receptor 9; Chemokine receptor 9; Chemokine receptor CCR 10; Chemokine receptor CCR 9; Chemokine receptor CCR-10; Chemokine receptor CCR-9; Chemokine receptor CCR10; Chemokine receptor CCR9; Chemokine receptor D6; Chemokine-binding protein 2; Chemokine-binding protein D6; CMKBR 9; CMKBR9; D6; hD6; MGC126678; MGC138250.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Chemokine Receptor D6
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Chemokine Receptor D6 is a member of the C-C (β chemokine) G protein-coupled receptor family. This family is characterized by a pair of adjacent cysteine residues. C-C chemokine receptor family members also include CKR-1, CKR-2A, CKR-2B, CKR-3, CKR-4, CKR-5, CKR-6, CKR-7, CKR-8, CKR-9, CKR-10, CCXCKR, Bonzo, BOB (brother of Bonzo) and Duffy blood group antigen. Each of these receptors are G protein-coupled, seven pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to sites of inflammation. Chemokine Receptor D6 acts as a receptor for various C-C type chemokines, including SCYA2/MCP-1, SCY3/MIP-1-α, SCYA5/RANTES and SCYA7/MCP-3. It is expressed primarily in placental tissues and fetal liver, but is also detected in lymphatic endothelial cells, lymph nodes and mucosa of the small and large intestines.

Function:
Receptor for C-C type chemokines including SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node. Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 1238 Human

Omim: 602648 Human

SwissProt: O00590 Human

Unigene: 146346 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片
Blank control: Molt4. 
Primary Antibody (green line): Rabbit Anti-Chemokine Receptor D6 antibody (bs-13897R-FITC) 
Dilution: 1μg /10^6 cells; 
Isotype Control Antibody (orange line): Rabbit IgG .
Dilution: 1μg /test. 
Protocol
The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed

趋化因子受体D6是C-C（β趋化因子）G蛋白偶联受体家族的成员。该家族的特征在于一对相邻的半胱氨酸残基。C-C趋化因子受体家族成员还包括CKR-1、CKR-2A、CKR-2B、CKR-3、CKR-4、CKR-5、CKR-6、CKR-7、CKR-8、CKR-9、CKR-10、CCXCKR、Bonzo、BOB(Bonzo的兄弟)和Duffy血型抗原。这些受体中的每一个都是G蛋白偶联的，七个跨膜结构域蛋白，其主要生理作用是使T细胞和吞噬细胞趋化至炎症部位。趋化因子受体D6是多种C-C类趋化因子的受体，包括SCYA2/MCP-1、SCY3/MIP-1-α、SCYA5/RANTES和SCAY7/MCP-3。它主要表达于胎盘组织和胎肝，但也在小肠和大肠的淋巴内皮细胞、淋巴结和粘膜中检测到。