GRB7 polyclonal antibody
产品名称： GRB7 polyclonal antibody
英文名称： GRB7 polyclonal antibody
产品编号： PAB6157
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of GRB7.
- Immunogen:
- A synthetic peptide corresponding to human GRB7.
- Sequence:
- ELDLSPPHLSSSPE-C
- Host:
- Goat
- Theoretical MW (kDa):
- 59.7
- Reactivity:
- Human
- Specificity:
- This antibody recognizes the longer isoform of this protein in A431 lysate.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
Western blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains.
Margolis B, Silvennoinen O, Comoglio F, Roonprapunt C, Skolnik E, Ullrich A, Schlessinger J.Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):8894-8.
- Applications
- Western Blot (Cell lysate)
- GRB7 polyclonal antibody (Cat # PAB6157) staining (2 ug/mL) of A-431 lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
- Entrez GeneID:
- 2886
- Protein Accession#:
- NP_005301
- Gene Name:
- GRB7
- Gene Alias:
- -
- Gene Description:
- growth factor receptor-bound protein 7
- Omim ID:
- 601522
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Alternative splicing results in multiple transcript variants encoding different isoforms, although the full-length natures of only two of the variants have been determined to date. [provided by RefSeq
- Other Designations:
- OTTHUMP00000164352
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