FITC标记的核基质蛋白3抗体
产品名称： FITC标记的核基质蛋白3抗体
英文名称： Anti-Matrin 3/FITC
产品编号： HZ-5141R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-Matrin 3/FITC Conjugated antibody
FITC标记的核基质蛋白3抗体
| 英文名称 | Anti-Matrin 3/FITC |
| 中文名称 | FITC标记的核基质蛋白3抗体 |
| 别 名 | MATR3; Matrin3; Matrin-3; KIAA0723; Matr3; MATR3_HUMAN; MPD2; VCPDM. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 免疫学 染色质和核信号 信号转导 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 95kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Matrin 3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Matrin 3 (MATR 3) is an internal nuclear matrix protein that may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer MATR 3 may play a role in nuclear retention of defective RNAs. MATR3 forms part of complex consisting of SFPQ, NONO and MATR3. The protein contains 1 matrin type zinc finger and 2 RRM (RNA recognition motif) domains. Two transcript variants encoding the same protein have been identified for this gene. Function: May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Subunit: Part of complex consisting of SFPQ, NONO and MATR3. Interacts with EIF2C1 and EIF2C2. Subcellular Location: Nucleus matrix. DISEASE: Defects in MATR3 are the cause of myopathy distal type 2 (MPD2) [MIM:606070]; also called vocal cord and pharyngeal dysfunction with distal myopathy (VCPDM). MPD2 is a muscular disorder characterized by distal weakness, with onset in hands and feet, associated with vocal cord and pharyngeal weakness causing a nasal voice and swallowing disorders. Similarity: Contains 1 matrin-type zinc finger. Contains 2 RRM (RNA recognition motif) domains. Database links: Entrez Gene: 9782 Human Entrez Gene: 17184 Mouse Entrez Gene: 29150 Rat Omim: 164015 Human SwissProt: P43243 Human SwissProt: Q8K310 Mouse SwissProt: P43244 Rat Unigene: 268939 Human Unigene: 595110 Human Unigene: 215034 Mouse Unigene: 482118 Mouse Unigene: 29774 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
苦参素3（MATR 3）是一种内核基质蛋白，可在转录中发挥作用，或与其他核基质蛋白相互作用，形成内部纤维颗粒网络。与SFPQ-NONO异构体MATR相关联，5月3日在缺陷RNA的核保持中起作用。Mord3是由SFPQ、NONO和Mord3组成的复合物的一部分。蛋白质含有1个苦参碱锌指和2个RRM（RNA识别基序）结构域。两个编码相同蛋白的转录变体已被鉴定为该基因。