MAOB Pre-design Chimera RNAi
产品名称: MAOB Pre-design Chimera RNAi
英文名称: MAOB Pre-design Chimera RNAi
产品编号: H00004129-R01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Homo sapiens monoamine oxidase B (MAOB), nuclear gene encoding mitochondrial protein, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_000898
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 4129
- Gene Name:
- MAOB
- Gene Alias:
- MGC26382
- Gene Description:
- monoamine oxidase B
- Omim ID:
- 309860
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq
- Other Designations:
- MAO, brain,MAO, platelet,adrenalin oxidase,tyramine oxidase
- Related Disease
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Asperger Syndrome
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Basal Ganglia Diseases
- Body Weight
- Cardiovascular Diseases
- Cognition
- Combat Disorders
- Conduct Disorder
- Depressive Disorder, Major
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Disease Progression
- Dyskinesia, Drug-Induced
- Edema
- Fatigue Syndrome, Chronic