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上海信裕生物科技有限公司
SQLE 抗体

SQLE 抗体

商家询价

产品名称： SQLE 抗体

英文名称： SQLE Antibody

产品编号： XY 12544-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 SQLE 抗体Applications

In-house applications ELISA, WB, IHC, IP, IF     Application not tested? Please see our Guarantee.
Published applications WB Publications 6 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Hamster, human, mouse
Images
Prev12NextView more validation data
  • 12544-1-AP;A549 cellsA549 cells were subjected to SDS PAGE followed by western blot with 12544-1-AP(SQLE antibody) at dilution of 1:300
  • 12544-1-AP;A549 cellsIP Result of anti-SQLE (IP:12544-1-AP, 3ug; Detection:12544-1-AP 1:300) with A549 cells lysate 920ug.
  • 12544-1-AP;human breast cancer tissueImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using 12544-1-AP( SQLE Antibody) at dilution of 1:50 (under 10x lens)
  • 12544-1-AP;human breast cancer tissueImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using 12544-1-AP( SQLE Antibody) at dilution of 1:50 (under 40x lens)
  • 12544-1-AP;PC-3 cellsImmunofluorescent analysis of PC-3 cells using 12544-1-AP( SQLE Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in A549 cells, HEK-293 cells
Positive IP detected in A549 cells
Positive IHC detected in Human breast cancer tissue, human prostate cancer tissue
Positive IF detected in PC-3 cells
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:20-1:200
 SQLE 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information SQLE 抗体
Immunogen SQLE fusion protein ag3266 Full name Squalene epoxidase
Calculated molecular
weight		 574aa,64 kDa Observed molecular 
weight		 64kd
GenBank accession 
number		 BC017033 Gene ID (NCBI) 6713
Gene symbol SQLE Synonyms ERG1, FLJ30795, SE, SQLE, squalene epoxidase, Squalene monooxygenase
Background

SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd. SQLE 抗体

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XY317Hu21 羧肽酶A4(CPA4)单克隆抗体 Monoclonal Antibody to Carboxypeptidase A4 (CPA4) Homo sapiens (Hukl)

XY320Ra21 羧肽酶B1(CPB1)单克隆抗体 Monoclonal Antibody to Carboxypeptidase B1, Tissue (CPB1) Rattus norvegicus (Rat)

XY322Hu21 羧肽酶E(CPE)单克隆抗体 Monoclonal Antibody to Carboxypeptidase E (CPE) Homo sapiens (Hukl)

XY324Ra21 羧肽酶N2(CPN2)单克隆抗体 Monoclonal Antibody to Carboxypeptidase N2 (CPN2) Rattus norvegicus (Rat)

XY326Hu21 羧肽酶Z(CPZ)单克隆抗体 Monoclonal Antibody to Carboxypeptidase Z (CPZ) Homo sapiens (Hukl)

XY331Hu21 细胞维甲酸结合蛋白2(CRABP2)单克隆抗体 Monoclonal Antibody to Cellular Retinoic Acid Binding Protein 2 (CRABP2) Homo sapiens (Hukl)

XY332Hu21 复合素2(CPLX2)单克隆抗体 Monoclonal Antibody to Complexin 2 (CPLX2) Homo sapiens (Hukl)

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XY339Hu21 半胱氨酸丰富分泌蛋白2(CRISP2)单克隆抗体 Monoclonal Antibody to Cysteine Rich Secretory Protein 2 (CRISP2) Homo sapiens (Hukl)

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XY358Hu21 热休克蛋白β6(HSPβ6)单克隆抗体 Monoclonal Antibody to Heat Shock Protein Beta 6 (HSPb6) Homo sapiens (Hukl)

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XY360Hu21 Cullin 9蛋白(CUL9)单克隆抗体 Monoclonal Antibody to Cullin 9 (CUL9) Homo sapiens (Hukl)

XY368Hu21 肉毒碱棕榈酰基转移酶1A(CPT1A)单克隆抗体 Monoclonal Antibody to Carnitine Palmitoyltransferase 1A, Liver (CPT1A) Homo sapiens (Hukl)

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