FBXO6抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
FBXO6抗体

FBXO6抗体

商家询价

产品名称： FBXO6抗体

英文名称： FBXO6Antibody

产品编号： XY11830-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 FBXO6抗体

Applications
In-house applications ELISA, IHC, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
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  • 11830-1-AP;mouse liver tissuemouse liver tissue were subjected to SDS PAGE followed by western blot with 11830-1-AP(FBXO6 antibody) at dilution of 1:300
  • 11830-1-AP;human gliomasImmunohistochemical of paraffin-embedded human gliomas using 11830-1-AP(FBXO6 antibody) at dilution of 1:50 (under 10x lens)
Positive WB detected in Mouse liver tissue, Transfected HEK-293 cells
Positive IHC detected in Human gliomas tissue
Recommended dilution WB : 1:200-1:1000
IHC : 1:20-1:200
 FBXO6抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information FBXO6抗体
Immunogen FBXO6 fusion protein ag2400 Full name F-box protein 6
Calculated molecular
weight		 293aa,34 kDa Observed molecular 
weight		 35 kDa
GenBank accession 
number		 BC020880 Gene ID (NCBI) 26270
Gene symbol FBXO6 Synonyms F box only protein 6, F box protein 6, F box/G domain protein 2, FBG2, FBS2, FBX6, Fbx6b, FBXO6
Background

FBXO6(F-box only protein 6 ) is also named as FBG2, FBS2, FBX6 and belongs to the F-box protein family. It can regulate Chk1 ubiquitination and degradation in both normally cycling cells and during replication stress. This protein is mainly detected in the cytoplasm in both cultured cells and in tumor tissues. Its expression is a predictive biomarker of tumor responsiveness to the important anticancer drugs.(PMID:19716789). FBXO6 can inhibit the anaphase promoting complex (cyclosome APC) and prevent mitotic exit in cytostatic factor (CSF) arrested eggs as a mitotic regulator. FBXO6抗体

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