CDKN2C MaxPab mouse polyclonal antibody (B02)
产品名称： CDKN2C MaxPab mouse polyclonal antibody (B02)
英文名称： CDKN2C MaxPab mouse polyclonal antibody (B02)
产品编号： H00001031-B02
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human CDKN2C protein.
- Immunogen:
- CDKN2C (NP_001253, 1 a.a. ~ 168 a.a) full-length human protein.
- Sequence:
- MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of CDKN2C expression in transfected 293T cell line (H00001031-T02) by CDKN2C MaxPab polyclonal antibody.
Lane 1: CDKN2C transfected lysate(18.48 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of purified MaxPab antibody to CDKN2C on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Entrez GeneID:
- 1031
- GeneBank Accession#:
- NM_001262
- Protein Accession#:
- NP_001253
- Gene Name:
- CDKN2C
- Gene Alias:
- INK4C,p18,p18-INK4C
- Gene Description:
- cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
- Omim ID:
- 603369
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq
- Other Designations:
- CDK6 inhibitor p18,OTTHUMP00000009730,OTTHUMP00000009731,OTTHUMP00000046546,cyclin-dependent inhibitor,cyclin-dependent kinase 4 inhibitor C,cyclin-dependent kinase 6 inhibitor p18,cyclin-dependent kinase inhibitor 2C
- Gene Pathway
- Related Disease
- Breast cancer
- Breast Neoplasms
- Disease Progression
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Malignant melanoma
- Melanoma
- Multiple endocrine neoplasia
- Multiple Endocrine Neoplasia Type 1
- Multiple Myeloma
- Neoplasm Invasiveness
- Neoplasm Recurrence, Local
- Neoplasms, Second Primary
- Ovarian cancer
- Ovarian Neoplasms